Reference Ranges Library¶
A consolidated library of species-specific reference intervals for Migibio FICT assays. Values are representative adult reference ranges; individual labs should verify against their own population and follow the package insert (IFU) for each assay.
1. Canine Reference Ranges¶
| Analyte | Category | Reference Range | Unit |
|---|---|---|---|
| CRP | Inflammation | < 10 | mg/L |
| SDMA | Renal | 0–14 | µg/dL |
| Creatinine | Renal | 0.5–1.8 | mg/dL |
| NT-proBNP | Cardiac | < 900 | pmol/L |
| T4 (Total) | Thyroid | 1.0–4.0 | µg/dL |
| TSH | Thyroid | 0–0.6 | ng/mL |
| Cortisol (basal) | Adrenal | 2–6 | µg/dL |
| Progesterone | Reproductive | 0–2 (anestrus) | ng/mL |
2. Feline Reference Ranges¶
| Analyte | Category | Reference Range | Unit |
|---|---|---|---|
| SAA | Inflammation | < 5 | µg/mL |
| SDMA | Renal | 0–14 | µg/dL |
| Creatinine | Renal | 0.8–2.4 | mg/dL |
| NT-proBNP | Cardiac | < 100 | pmol/L |
| T4 (Total) | Thyroid | 1.0–4.0 | µg/dL |
| fPL (pancreatic lipase) | Pancreatic | < 3.5 | µg/L |
3. Notes on Interpretation¶
- Reference ranges are population statistics, not absolute thresholds. Values near the boundary warrant clinical correlation.
- Breed, age, and sex can shift normal ranges (e.g., sighthounds have lower creatinine/T4).
- Pre-analytical factors (hemolysis, lipemia, fasting status) affect specific analytes — follow IFU specimen requirements.
4. IRIS CKD Staging (SDMA + Creatinine)¶
| IRIS Stage | Creatinine (canine) | SDMA (canine/feline) |
|---|---|---|
| Stage 1 | < 1.4 mg/dL | < 18 µg/dL |
| Stage 2 | 1.4–2.8 mg/dL | 18–35 µg/dL |
| Stage 3 | 2.9–5.0 mg/dL | 36–54 µg/dL |
| Stage 4 | > 5.0 mg/dL | > 54 µg/dL |
5. FAQ¶
Are these ranges universal across all analyzers? No. Reference ranges can vary by method and instrument. The values here are for the Migibio FICT platform; verify against your own analyzer and local population.
Why do dogs and cats have different NT-proBNP cutoffs? Cardiac size, physiology, and normal peptide levels differ between species — feline NT-proBNP reference (< 100 pmol/L) is much lower than canine (< 900 pmol/L).
Where do I find the authoritative cutoff for a specific assay? The product IFU is the legally controlling document. This library is a technical reference.
6. Authoritative Sources¶
- IRIS (International Renal Interest Society) — SDMA and creatinine CKD staging values.
- ACVIM (American College of Veterinary Internal Medicine) — endocrine and cardiac interpretation guidance.
For detailed per-analyte data cards, see Biomarker Data. For validation methodology, see the research center.
Authored by: Migibio Clinical & Scientific Affairs, Guangzhou Magic Biotech Co., Ltd.
Reviewed by: Migibio R&D Quality Committee
Last updated: 2026-08-13
Disclosure: Migibio (Guangzhou Magic Biotech Co., Ltd.) is the manufacturer of the FIA680/FIA880 analyzers and FICT reagents referenced in this content. See our Editorial & Review Policy.